AP39 THROUGH AMPK-ULK1-FUNDC1 PATHWAY REGULATES MITOPHAGY, INHIBITS PYROPTOSIS, AND IMPROVES DOXORUBICIN-INDUCED MYOCARDIAL FIBROSIS

AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis

Summary: Doxorubicin induces coffee table myocardial injury and fibrosis.Still, no effective interventions are available.AP39 is an H2S donor that explicitly targets mitochondria.This study investigated whether AP39 could improve doxorubicin-induced myocardial fibrosis.Doxorubicin induced significant myocardial fibrosis while suppressing mitophagy-

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IDENTIFICATION OF ANISAKID NEMATODE L3 LARVAE INFECTION ON SKIPJACK TUNA (KATSUWONUS PELAMIS L.) FROM KUPANG WATERS, EAST NUSA TENGGARA OF INDONESIA

The larvae of Anisakis were living Sofa Cushions parasites and made marine mammals, birds and reptiles the definitive host.Identification of Anisakis larvae using morphological observation methods will be difficult, especially if there are only a few samples that can be identified.PCR is an identification method using DNA from a small sample quanti

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